Mohamed, Moustafa (2025) Different therapeutic approaches to Zenker diverticulum: A retrospective comparative study between the flexible endoscopic method using needle knife and the rigid endoscopic method using laser in terms of effectiveness, complications and recurrence rates. PhD, Universität Oldenburg.
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Abstract
Zenker’s diverticulum is an outpouching at the pharyngoesophageal junction causing dysphagia, regurgitation and aspiration. Myotomy may be performed by open, rigid or flexible endoscopy. This retrospective study compared flexible needle‑knife endoscopy (gastroenterology) and rigid laser myotomy (ENT). From 2009–2021, 136 patients were treated (88 flexible, 48 rigid). Flexible endoscopy showed shorter procedure time and hospitalization (p < 0.05). Complication and recurrence rates were similar, but subjective symptom improvement was higher (88.7% vs. 65.5%; p < 0.05). Flexible endoscopy may provide greater effectiveness with comparable safety.
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Das Zenker-Divertikel ist eine Ausstülpung am pharyngoösophagealen Übergang und verursacht Dysphagie und Aspiration. Die Therapie erfordert eine Myotomie. Diese retrospektive Studie verglich flexible Nadelmesser-Endoskopie und starre Laser-Myotomie. Es wurden 136 Patienten behandelt (88 flexibel, 48 starr). Die flexible Methode zeigte kürzere Eingriffs- und Krankenhausdauer (p < 0.05). Komplikations- und Rezidivraten waren ähnlich, jedoch berichteten mehr Patienten der flexiblen Gruppe eine subjektive Symptomverbesserung (88,7 % vs. 65,5 %; p < 0.05). Die flexible Endoskopie erscheint bei ähnlichem Sicherheitsprofil effektiver.
| Item Type: | Thesis (PhD) |
|---|---|
| Uncontrolled Keywords: | Zenker diverticulum, Rigid endoscopy, Flexible endoscopy |
| Divisions: | Faculty of Medicine and Health Sciences > Department of Human Medicine |
| Date Deposited: | 27 Nov 2025 09:40 |
| Last Modified: | 27 Nov 2025 09:40 |
| URI: | https://oops.uni-oldenburg.de/id/eprint/7310 |
| URN: | urn:nbn:de:gbv:715-oops-73917 |
| DOI: | |
| Nutzungslizenz: |
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